• Beyond sepsis overprescribing antibiotics and the rise of an

  2018-10-30

  

  Beyond sepsis, overprescribing pimaricin and the rise of antimicrobial resistance is of considerable concern. The O\'Neill report, which provides recommendations for tackling drug-resistant infections globally, advises developing diagnostics for bacterial infections to guide the use of antimicrobia

• br Introduction Influenza comprises a substantial portion of

  2018-10-29

  

  Introduction Influenza comprises a substantial portion of morbidity and mortality caused by acute respiratory infections, which are the fourth leading cause of death and the second highest cause of years of life lost (Organization, 2014; Radin et al., 2012; Nair et al., 2011). Severe influenza di

• A total of m z were identified and attributed

  2018-10-29

  

  A total of 62m/z were identified and attributed to 32 different molecular species corresponding to three intact and whole proteins and 58 peptides from 29 proteins (Supplementary Table 2). Forty-five of these peptides presented tryptic or semi-tryptic cleavages, suggesting protease activities by tr

• br Data experimental design materials and methods

  2018-10-29

  

  Data, experimental design, materials and methods Boron (B)-tolerant ‘Xuegan’ (Citrus sinensis) and B-intolerant ‘Sour pummelo’ (Citrus grandis) seedlings were used to investigate the effects of B-toxicity on leaf proteomics. Plant culture and B treatments were performed as described previously [1

• br Experimental design materials and methods

  2018-10-29

  

  Experimental design, materials and methods Mobility Retardation of NCALD (and other NCS proteins) in native gels has been documented and the retardation was directly dependent on the concentration of calcium [1,2]. Electrophoreses in native gels and analyses were carried out as described [1]. E

• It has been reported that a high concentration

  2018-10-29

  

  It has been reported that a high concentration of palmitate, the most abundant dietary saturated fatty MLN 9708 (SFA), induces apoptosis and insulin resistance in skeletal muscle cells through the activation of PKC and NFκ-B, increase of oxidative stress and mitochondrial dysfunction, etc. [5–8]. T

• The second characteristic of the

  2018-10-29

  

  The second characteristic of the present method includes using the rate constant (k) of a first-order reaction equation with correction factor to determine catalase activity. The rate constant of a first-order reaction (k) is used to determine catalase activity due to the abnormal kinetics of catala

• Current voltage I V characterization was conducted

  2018-10-29

  

  Current–voltage (I–V) characterization was conducted using a Keithley 2400 source measurement apparatus in a four-wire setup in ambient EPZ5676 with an ORIEL solar simulator (class ABA) at AM 1.5G. A silicon reference cell (PV Measurements, Inc. 20mm×20mm) was used for the calibration of the illumin

• Fig demonstrates cell damage induced by ultra

  2018-10-29

  

  Fig. 2 demonstrates cell damage induced by ultra-sonication and evaluated by estimation of the total protein content of the cell suspensions. The data demonstrates that ultra-sonication of GSK J4 induces varying degrees of cell damage directly proportional to the duration of ultra-sonication repres

• It is important to recognize

  2018-10-29

  

  It is important to recognize, however, that documenting the presence of SES-associated neural effects alone is not sufficient to support this formulation. While lower-SES children may be deprived of certain enriching experiences, they may also have other experiences which are less often considered.

• Although it has been established that many of the

  2018-10-29

  

  Although it has been established that many of the neural systems involved in romantic love and sex undergo significant structural, connectivity, and functional transformation during puberty, little is known about how this intersects with a normative romantic and sexual developmental trajectory. Inte

• In summary our findings suggest that in late

  2018-10-29

  

  In summary, our findings suggest that in late childhood and adolescence, the amPFC and IPL/IPS play a role as integrative regions with high hierarchical positions within the whole-brain network. Furthermore, we showed that disruptions in the hierarchical position of the IPS are associated with psych

• br Materials and methods br Discussion Previous

  2018-10-29

  

  Materials and methods Discussion Previous studies have documented the sensitivity of anti-ICS IIF testing in patients with pemphigus to be approximately 81–90%, the current study obtained similar results. The substrate used in IIF greatly influences the sensitivity of this test. Zagorodniuk et

• In previous papers global IED

  2018-10-29

  

  In previous papers, global IED effects and possible protection concepts were discussed [1,2,7,9]. This work is based on these results and summarises them in a form of an engineering software tool called PVIED (Protection of Vehicles against IED). The emphasis was put on modelling the momentum transf

• En apareci en la revista el asombroso texto The Five

  2018-10-29

  

  En 1993, apareció en la revista el asombroso texto “The Five Sexes: Why Male and Female Are Not Enough” de Anne Fausto-Sterling sobre la extraña presencia de indicadores biológicos de los dos sexos en ciertos cuerpos. Para ese entonces, el movimiento intersexual había comenzado a perfilarse como un

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