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In addition to CAF in
2019-06-20
In addition to CAF in the primary tumour microenvironment, it is tempting to speculate that fibroblasts within the bone itself may play a role in the establishment of metastatic deposits. Fibroblasts form a major component of the bone marrow stroma and regulate haematopoiesis by secreting a range of
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Vaccinated individuals might represent a safer source of hyp
2019-06-20
Vaccinated individuals might represent a safer source of hyperimmune serum. Two vaccine candidates will be tested soon in west Africa. If serum from vaccinated individuals has neutralising activity against the virus in cell models, this serum could be used as adjuvant therapy for EVD. In parallel, a
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What can be done to reduce morbidity
2019-06-19
What can be done to reduce morbidity and mortality in HEU infants? Notably, a third of all mortality in the Botswana trial occurred early, before randomisation. Similarly, in a trial of more than 14 110 infants in Zimbabwe, done in the pre-MTCT-prevention era, HIV-exposed uninfected infants had 50%
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br Methods This prospective study was conducted
2019-06-19
Methods This prospective study was conducted at the Zekai Tahir Burak Woman\'s Health, Research and Education Hospital, Ankara, Turkey between April 2009 and August 2009. The study was approved by the local Ethics Committee of the hospital, and an informed consent was signed by all patients befor
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br Interaction between MSCs and immune cells MSCs have also
2019-06-19
Interaction between MSCs and immune cells MSCs have also been shown to possess broad immunoregulatory capabilities and are capable of influencing both adaptive and innate immune responses. MSCs inhibit immune buy SF1670 proliferation and maturation and suppress immune reactions both in vitro and
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br Catheter ablation A reentry circuit is supported
2019-06-19
Catheter ablation A reentry circuit is supported by complex anatomy and a thick and/or damaged myocardium; thus, high-energy RF application is usually required to create the conduction block line through the critical isthmus of the reentry circuit in patients after ToF repair. A large-tip (8mm) a
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For the relationship between the PVAB
2019-06-19
For the relationship between the PVAB and FFRWs, setting the PVAB period as short as possible is considered optimal, because not all patients necessarily have problems with FFRWs [4,6]. However, the Medtronic pacemakers investigated in this study had minimum PVAB values as short as 110ms or 130ms, w
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In focal coronary spastic angina
2019-06-19
In focal coronary spastic angina, intravascular ultrasound was reported to detect intima–media complex thickening and an increased sonolucent zone [16,17], and OCT can detect intimal thickening with low lipid and calcium deposits [18], which are believed to reflect neointimal hyperplasia subsequent
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Oligomycin Complex br Conclusion br Financial support This r
2019-06-19
Conclusion Financial support This research was supported by a grant from the ׳Gerencia de Salud, Consejería de Sanidad, Junta de Castilla y Leon׳ [GRS 308/A/08] and ‘Caja Burgos Foundation’ [Convocatoria 2007].The funding organization had no involvement in the study. Clinical trial registra
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Most forms of AVNRT are created by reentry
2019-06-19
Most forms of AVNRT are created by reentry between two (or more) atrial connections to the AV node. The fast AV nodal pathway (shortest conduction time) is formed by transitional cells crossing the tendon of Todaro superiorly. Two slow AV nodal pathways are formed by the rightward and leftward infer
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A decreasing trend in CRT D
2019-06-19
A decreasing trend in CRT-D implantation has been reported recently, based on the database from the National Inpatient Sample in the USA [20]. They found that advancing age and an increasing comorbidity burden were associated with a reduced likelihood of CRT-D, and speculated that the decline in CRT
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Having to seek various approvals with no
2019-06-19
Having to seek various approvals, with no communication between RECs and no plan for which committee\'s decisions take priority, can lead to research bottlenecks. Many RECs, particularly those in low-income and middle-income countries (LMICs), have long turnaround times, perhaps because of infrequen
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No se trata de una simple par frasis de
2019-06-19
No se trata de una simple paráfrasis de “ellos saben muy bien lo que hacen, pero aun así lo hacen”, porque al interpretar el sentido que asume el entramado social, relacional, como depositario de las “acciones” reformistas estatales, es evidente que existe una necesidad por estructurar la propia rea
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br En Argentina la pobreza como categor a
2019-06-19
En Argentina, la pobreza como categoría organizadora de la intervención estatal triunfó en la década de los ochenta. Hacia 1984 se publicó un informe sobre La pobreza en Argentina order Pexmetinib la vez que su medición comenzó a constituir un asunto de Estado y un diagnóstico prevaleciente articu
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Este trabajo llama la atenci
2019-06-19
Este trabajo llama la atención sobre dos volúmenes de poesía (, de 1916, y , de 1967) ligados de modo estrecho Ac-DEVD-AFC dos momentos clave de la historia provincial: por un lado, el año del Centenario de la Independencia Nacional —cuya declaración había tenido lugar, como es sabido, en 1816 preci
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