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Pahlavanzadeh and Fakouri Baygi employed PC SAFT EoS to
2019-09-12
Pahlavanzadeh and Fakouri-Baygi [6] employed PC-SAFT EoS to predict the Praziquantel of carbon dioxide by aqueous MEA solutions. They used the ideal form of Smith–Missen algorithm to calculate liquid phase concentrations. The results illustrate acceptable accuracies so that the AAD was achieved equ
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Cordycepin Yet the standards fall back on the development pr
2019-09-12
Yet, the standards fall back on the development process with justification. As shown by Littlewood and Strigini (1993), the extent to which the reliability of software (both OTS and bespoke) can be proved by testing is severely limited––not because appropriate tests cannot be devised, but because ad
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br Use of recombinant collagen to study DDR collagen interac
2019-09-12
Use of recombinant collagen to study DDR–collagen interactions Synthetic peptides have proven highly valuable in replicating the characteristics of collagen and in defining the sites on collagen essential for binding and studying protein–collagen interactions. There are, however, disadvantages to
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E cadherin is an adhesive Ca
2019-09-12
E-cadherin is an adhesive Ca2+ dependent transmembrane protein mediating tight and strong cell-cell adhesion through homophilic interactions. There is strong evidence in favour of the major role of E-cadherin in melanocytes adhesion to keratinocytes in the Gemcitabine kinase (Tang et al., 1994). The
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A previous study reported that it is unlikely
2019-09-11
A previous study reported that it is unlikely that silkworm mounts a general type of immune response to all viruses (Liu et al., 2015). It is not clear whether there is a common pattern of host regulation for silkworm viruses. Spry is a general inhibitor of receptor tyrosine kinases (RTKs), which is
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Recently roflumilast has been approved
2019-09-11
Recently, roflumilast has been approved as the first selective PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease (COPD) [2]. Roflumilast has been suggested to target several different pathogenetic mechanisms, including inflammation, fibrotic, emphysematous and vascular remode
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In human neuroblastoma SH SY
2019-09-11
In human neuroblastoma SH-SY5Y filipin and in lymphoma Jurkat cells, Yamanaka et al. [56] showed that exogenously added 24(S)-hydroxycholesterol could be efficiently esterified by ACAT1. These results suggest that both ACAT1 and ACAT2 can control the oxysterol levels by directly esterifying them, i
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br Experimental Procedures br Author Contributions br Acknow
2019-09-11
Experimental Procedures Author Contributions Acknowledgments Introduction Oxysterols came to prominence in the late 1970\'s with the oxysterol hypothesis which proposed that the suppressive effect of cholesterol on its own synthesis is mediated through oxysterols not by cholesterol itsel
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FOX proteins constitute a large class of
2019-09-11
FOX proteins constitute a large class of transcription factors with multiple functions, from development and organogenesis to regulation of metabolic and immune functions. The Fox transcription factor is characterized by a 100-amino-acid wing helix or forkhead DNA-binding domain. In addition, the FO
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E is encoded by the largest and most conserved open
2019-09-11
E1 is encoded by the largest and most conserved open-reading frame (ORF) of the PV genome. The protein ranges in size from 600 to 650 amino acids, depending on the PV type. Overall, the protein can be divided into three functional segments: an N-terminal regulatory region that is essential for optim
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Because conventional KO mice die within h
2019-09-11
Because conventional KO mice die within 24h of birth, it is difficult to analyze higher Cyanidin Chloride clinical functions using them. Therefore, in this study, we generated brain-specific conditional DGKδ-KO mice and used these mice to perform behavioral and pharmacological tests. Results
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Quantum walks can be connected to
2019-09-11
Quantum walks can be connected to extended CMV matrices as follows. If all Verblunsky coefficients with even index vanish, then the extended CMV matrix becomes which resembles the matrix representation U. One may notice, however, that in the extended CMV matrix , whereas in the quantum walk matri
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Recently several Pt IV complexes as prodrugs
2019-09-11
Recently, several Pt(IV) complexes as prodrugs have been designed and studied to enhance anti-tumor efficacy of traditional Pt(II) drugs, improving their cellular uptake and blood-circulation time [26], [27], [28], [29]. Compared with their Pt(II) counterparts, six-coordinated Pt(IV) complexes with
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A widely accepted mechanism to differentiate hESCs into card
2019-09-11
A widely accepted mechanism to differentiate hESCs into cardiomyocytes is through perturbation of the canonical Wnt/β-catenin pathway. Initial Wnt activation is required to form the UNC 0631 [3]. Thereafter, it is believed that inhibition of the canonical Wnt/β-catenin pathway is pivotal for cardiom
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In some pancreatic and non pancreatic tissues the chloride
2019-09-11
In some pancreatic and non-pancreatic tissues, the chloride and calcium channels are heavily regulated by phosphorylation by protein kinases, such as PKC, cyclic AMP-dependent protein kinase (PKA), PKCaMKII, PI3K and protein tyrosine kinases [7,36,37]. Since the interaction of triterpenes with recep
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