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MSG model is well characterized and widely
2023-09-15
MSG model is well characterized and widely used because it is not influenced by dietary components and because it mimics a lesion in the arcuate nucleus and lateral hypothalamus that can occur in chronic obese patients (Moraes et al., 2009, Purkayasta and Cai, 2013). High fat fed diet is amongst th
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br Material and methods br Results br Discussion Although
2023-09-15
Material and methods Results Discussion Although we were not able to detect 12/15-LOX mRNA in the lungs of 12/15-LOX knockout mice substantial amounts of 15-HETE could be detected in BALF. In fact, significant synthesis of 15-HETE in 12/15-LOX mice have been already reported [17]. The redun
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Glu Gln Asp and Asn the main amino acids
2023-09-15
Glu, Gln, Asp, and Asn, the main Voriconazole presented in the present study, are involved in nitrogen assimilation and transport processes within the plants. Furthermore, they are used to build up reserves during periods of nitrogen availability for subsequent use in growth, defense, and reproduct
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Alsterpaullone sale So far many independent studies
2023-09-15
So far, many independent studies have linked cholesterol metabolism–related genes with AD, either by showing associations with specific polymorphisms or with differential Alsterpaullone sale levels (Beecham et al., 2014, Blain and Poirier, 2004, Lambert et al., 2009, Lambert et al., 2013, Leduc et a
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Arecaidine but-2-ynyl ester tosylate The enzyme mediated ATP
2023-09-14
The enzyme-mediated ATP-sensing mechanism in zebrafish can be compared with previous studies in other animal species reporting that enzymatic conversion of chemicals in the peripheral olfactory organ results in either “activation” or “inactivation” of odorants and pheromones. In male silkmoth, the a
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As also found by Stolarski et al inclusion of
2023-09-14
As also found by Stolarski et al. [14], inclusion of N2O in the model is successful in reducing the effect of dynamics [13] in the lower stratosphere in the Northern Hemisphere (30–60°N in our case). The inclusion of N2O also decreased the error bars on the trend values, but the trend values still c
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A rational approach for the design
2023-09-14
A rational approach for the design of new steroid compounds as possible competitive inhibitors of CYP17 include chemical modification at C17 of the enzyme's natural substrates, pregnenolone (1) and progesterone (2), introducing groups with moderate to strong dipole properties at C20, such as oxime a
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br Materials and methods br Results br Discussion br Author
2023-09-14
Materials and methods Results Discussion Author contributions JH purified protein, performed vanadate inhibition experiments, crystallized, collected data, determined and refined the ATX-VO5 structure, analysed all the structures, prepared the displayed items and supervised ALHE; WJK con
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As the effects of baclofen on primary afferent activity
2023-09-14
As the effects of baclofen on primary afferent activity are not reproduced by GABAA receptor agonists like muscimol and isoguvacine, this ionotropic receptor may play minimal role in the modulation of primary afferent activity. However, it is important to note that post-synaptic GABAA receptors rema
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N,N-Dimethylsphingosine Many naphthoquinone derivatives have
2023-09-14
Many naphthoquinone derivatives have been previously obtained from fungi in the genus Fusarium isolated from various sources, F. oxysporum from the root of citrus (Nagia and El-Mohamedy, 2007), Fusarium sp. (No. b77) from the mangrove plant (Shao et al., 2010), F. solani and F. oxysporum from fibrou
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For all three fluorescent dyes used the double
2023-09-14
For all three fluorescent dyes used, the double-labeled UQ-bodies showed higher antigen responses. A plausible mechanism for the higher quenching observed for the double-labeled UQ-bodies is the dye-dye quenching due to H-dimer formation [19] between the two dyes introduced into the Fd and L chains.
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br Materials and methods br Results and discussion First we
2023-09-13
Materials and methods Results and discussion First, we examined whether hypothalamic Akt-mediated signaling pathways are regulated postprandially in chickens. Refeeding significantly (P AZD1390 concentrations significantly increased in chicks after 1 h of refeeding (958 ± 245% of 24 h-fasting
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PF-CBP1 hydrochloride Human testicular peritubular cells HTP
2023-09-13
Human testicular peritubular PF-CBP1 hydrochloride (HTPCs) are also the only human testicular cell type that can be isolated, cultured and studied in vitro (Albrecht et al., 2006, Mayerhofer, 2013). Results from recent studies indicate that their roles go beyond sperm transport and include immunolo
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To validate the identified phosphorylation sites
2023-09-13
To validate the identified phosphorylation sites in the mouse heart, we analyzed HEK 293T MRS1523 transfected with Adrb1 based on the hypothesis that protein residues phosphorylated both in vivo and in vitro are more likely to be physiologically relevant. All of the phosphorylation sites identified
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The following are the supplementary data
2023-09-13
The following are the supplementary data related to this article. Conflict of interest Acknowledgements Disclosure of interest Introduction Since the introduction of platinum-based chemotherapy, metastatic testicular cancer has become a curable disease and most testicular cancer patient
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